Meet Mary.

Mary experiences slow onset and intense, long-lasting THC side effects because she metabolizes THC slowly.

Mary tries a THC-infused chocolate to help manage her chemotherapy symptoms. After eating the chocolate, it takes a long time for her to feel anything. Then suddenly, she starts feeling waves and peaks of being high for nearly 24 hours. Mary has experienced slow onset of effect and intense, long-lasting THC side effects because she metabolizes THC slowly.

Does this sound like an experience you’ve had?

Metabolism is the body’s process of breaking down substances, using the component parts, and discarding the waste products. Like other common complex compounds, including food, THC is metabolized in the body.

If you metabolize THC too slowly, you may experience waves of intense side effects for a longer time than others. If you metabolize THC too quickly, you may experience diminished effects and require larger dosing to achieve your desired therapy outcomes.

Cannabis is personal.

Learn how Mary’s endocompatibility helped her choose a cannabinoid formulation that worked for her unique genotype and health goals.

Mary was living in an assisted living facility when she was diagnosed with carcinoma. She began chemotherapy treatment and it made her feel terrible. She felt fatigued all day and started losing her hair.  Mary also had severe changes in her appetite and lost 15 pounds in two months. 

One night at the assisted living facility, Mary was watching TV with her friend Sandy who was in remission from colon cancer. On the screen, a well-known doctor was talking about the therapeutic effects of cannabis for chemotherapy patients. Sandy agreed with the doctor’s opinion, and she told Mary about how cannabis helped her regain her appetite during her own chemo treatments.  

 Mary was hesitant to believe the doctor and her friend Sandy. She remembered her only experience with cannabis quite vividly. At a party nearly fifty years ago,  Mary smoked cannabis and didn’t like how she felt. She got too high and it ruined her night. Overall, Mary decided cannabis wasn’t for her, and she never tried it again. 

But  Mary trusted both the well-known doctor and her friend Sandy. 

She went to the local dispensary and talked to the budtender about her past experience. He nodded as if he fully understood and recommended a chocolate. He suggested she take a small piece first and take more as needed. 

Mary followed the budtender’s advice. She ate a small piece of the chocolate and waited an hour. 

When nothing happened, she took another small piece. 

Forty five minutes later,  Mary began to feel the effects. She was very high. She had anxiety, paranoia, and hallucinations for nearly twenty four hours. When the side effects finally began to wear off,  Mary regretted her decision to try cannabis therapy in the first place.

Mary told everyone at the assisted living facility to stay away from cannabis. She couldn’t imagine how it could be therapeutic for people like her.

When  Mary told Sandy about her experience, Sandy told Mary she could use her genetics to find the optimal ratios of cannabinoids and terpene profiles for her unique genotype. She encouraged  Mary to try an Endo·Aligned suggested formulation.

Mary reluctantly gave Endo·dna a try. She uploaded her Ancestry.com DNA results to Endo·dna’s website, and she received her Endo·Decoded Report and Endo·Aligned suggested formulations in minutes. She went over her reports in detail and was surprised to learn that she was a slow metabolizer of THC.

The next day, Mary used her Drug to Drug Interaction Report to make sure her standard medications wouldn’t interact with cannabis therapy. Then, she purchased the Endo·Aligned suggested formulations outlined on her Mydna.live health portal.

Mary bought a sublingual spray and it changed her entire cannabis experience. She was able to successfully incorporate cannabis into her wellness plan.  Mary recommends Endo·dna to all her friends undergoing cancer treatments.

Mary’s genetic predisposition.

Mary’s Endo·Decoded Report reveals that she is a slow metabolizer of THC.

Nearly 10% of the population share this genotype and are predisposed to impaired THC metabolism.  

If you share Mary’s genotype, you may experience problems dosing THC and may feel delayed or quickened onset.

This can lead to intense, long-lasting cannabis effects or quick, diminished therapeutic effects.

Endo·dna helps you discover the optimal CBD and THC products based on your own DNA.

  • Learn the most ideal ratios, methods and dosing for your body.
  • Know which terpenes and cannabinoids to seek out or to avoid.
  • Understand any risks or benefits from using cannabinoids.
  • Identify the specific products and brands most aligned with your genetics.

Your DNA is the key to unlocking your unique endocompatibility.

Download a sample of the Endo·Decoded DNA variance report and explore the possibilities it holds for you.

  • 57 Trait Reports.
  • Your Personalized Wellness Plan.
  • Endo·Aligned formulations suggestions.
  • Personalized prescription drug to drug interaction report.
  • Endo·Aligned Product Marketplace.

What your DNA can tell you about using CBD and cannabis for health and wellness.

Stress/Anxiousness and Cannabinoids

Pain and Cannabinoids

Sleep and Cannabinoids

THC and Metabolism

Opioid Dependance and Cannabinoids

Cannabinoids and Cognitive Function

Cannabinoids and Feelings of Depression

THC and Suspetibility To Psychosis

Information you need to know.

Endocanna Health, Inc. does not provide medical services. Endocanna Health’s reports are not to be considered or construed to be medical advice. The information contained in Endocanna Health’s reports is not intended to be substituted for the advice or consultation of a medical professional. Endocanna Health’s reports include cannabinoid compound suggestions based on your DNA and do not constitute medical advice, diagnosis, or consultation. Endocanna Health does not take responsibility for any side effects or medical issues that may arise from your use or consumption of the suggested cannabinoid compounds. Endocanna Health recommends consulting with a medical professional before use of any suggested cannabinoid compounds. Use of Endocanna Health’s DNA kit or information from Endocanna Health’s reports is not to be considered a medical treatment or a substitute for any treatment from a licensed healthcare provider. Endocanna Health makes no guarantees regarding your personal health, implied or otherwise, based on the results provided by Endocanna Health’s report.