There are lots of factors that can make you lose sleep. Maybe you suffer from chronic pain, or perhaps job stress has you tossing and turning in cold sweat every night.

What if, however, your genetics played a bigger role in insomnia than anyone suspected? Furthermore, what if there were safe, natural compounds you could use to specifically target the genes associated with sleep disorders?

Learn how to get a free EndoAligned Harlequin Hemp Oil Sweet Dreams tincture with an EndoDNA Kit.

What is the main cause of insomnia?

Insomnia can be caused by both environmental and genetic factors. In most cases, environmental factors trigger latent genetic tendencies toward insomnia.

Let’s list a few common causes of insomnia and explain how they might have underlying genetic causes:

  • Poor sleep habits
  • Anxiety or depression
  • Stress
  • Chronic pain
  • Neurological disorders

What causes people to sleep irregularly or fail to set aside enough time for proper sleep? While it’s ultimately your choice when you go to bed, impulsivity has a genetic basis, and people who are more impulsive tend to be less responsible.

Mood disorders like anxiety and depression are well known to run in families. Stress is related to both anxiety and depression, and your vulnerability to maladaptive stress responses is largely genetic.

The presence of certain genes will make you more susceptible to chronic inflammation and neuropathy, which are the most common causes of chronic pain. The genetic basis of neurological disorders is well-established. 

Is insomnia genetic or environmental?

Insomnia is both genetic and environmental. Regardless of the context, there is no simple answer to the “nature vs. nurture” argument.

Your genes are the raw materials life provides you with, and your environment is the artisan that transforms these raw materials into a finished product. It’s very difficult to meaningfully alter your genes, but you can rapidly change your environment by making different choices.

A wide definition of your environment also includes the substances you consume. By choosing to consume certain substances and avoid others, you can give directions to your environment as it shapes your genetic being.

In the case of insomnia, ingesting certain substances may help you “reprogram” the relationship between your environment and your genetics. With the right natural substances, you might be able to overcome genetic predispositions to insomnia.

Which genes are involved in sleep disorders?

Research indicates that variations in the MEIS1, DRD2, and DRD3 genes are involved in insomnia and other sleep disorders. You can treat insomnia with maximum effectiveness by using natural substances that target these gene variations.

How can I stop my insomnia?

There are dozens of different ways to address insomnia. Some basic hacks that might improve your situation include:

  • Adhering to a strict sleep schedule
  • Getting plenty of exercise
  • Limiting  your caffeine intake
  • Upgrading your mattress
  • Meditating to reduce stress
  • Taking prescription sleep medications
  • Trying natural sleep remedies

Without addressing the genetic factors that make you predisposed to insomnia, however, conventional approaches won’t reach the core of the issue. Prescription sleep medications simply overwhelm the components of your brain that keep you awake, many natural remedies don’t address your specific genetic profile, and lifestyle changes only scratch the surface.

Which natural substances are best for sleep?

There’s a surefire way to identify the plant-derived substances that will help you overcome insomnia at a genetic level:

  • Examine your genetic code for the presence of SNPs (“snips”) that cause insomnia
  • Ingest natural substances that target these specific gene snips

Using this method, you can identify substances that are guaranteed to alleviate your insomnia at the genetic level. At the same time, you can determine if certain plant-derived substances might cause adverse effects.

What are the best cannabinoids for sleep?

The Cannabis sativa plant is home to hundreds of different compounds. Only a handful of these substances are intoxicating, and every cannabis compound affects the human genome differently.

Recently, scientists have become keenly interested in the potential medicinal benefits of cannabis-specific substances called cannabinoids. Research suggests that the cannabinoids CBD, CBN, and THC might interact with the same segments of the human genome that cause insomnia.

Is CBD good for insomnia?

Viewed by some as a panacea, CBD has been widely researched for its potential sleep-inducing effects. Your unique genetic code might indicate CBD as an ideal non-intoxicating cannabinoid to use for insomnia.

Does CBN make you sleepy?

CBN is naturally formed when THC oxidizes, and cannabis aficionados have associated this cannabinoid with sound snoozing for decades. More peer-reviewed research needs to be conducted to fully determine the potential anti-insomnia effects of CBN, but our own investigations strongly implicate a connection between this non-intoxicating cannabinoid and the genes involved in insomnia.

Is THC good for sleep?

Research has been conducted into the sedative properties of THC. This cannabinoid might reduce the amount of time you spend in REM sleep, however, and genetically based adverse reactions to THC are relatively common.

What are the best terpenes for sleep?

In addition to cannabinoids, cannabis is also home to aromatic, delicious, and non-intoxicating compounds called terpenes. Based on scientific research, the terpenes myrcene, terpinolene, and linalool might have sleep-inducing properties.

Is myrcene good for sleep? 

Myrcene, which is also found in mangoes and hops, might increase the amount of time you spend asleep depending on your specific genetic profile.

Can terpinolene help with insomnia?

Research into terpinolene, which has an aroma reminiscent of every other terpene combined, indicates that this terpene might have sedative properties.

Does linalool make you sleepy?

Linalool is the terpene that gives lavender its distinctive floral aroma. Long used as a sedative in herbal medicine, contemporary research confirms linalool’s potential sleep-inducing effects.


Which essential oils are sedative?

Cannabis isn’t the only plant that might help with sleep by targeting your unique genome. Chamomile, lavender, and sandalwood extracts may also help you get rejuvenative rest each night by interfacing with the genes involved in insomnia.

Does chamomile essential oil help with sleep?

Just like chamomile tea, the essential oil extract of the chamomile plant also appears to have sedative properties.


Can lavender essential oil help with insomnia?

Commonly used as a natural sleep aid, lavender essential oil has been shown to help with sleep in clinical research.


Does sandalwood essential oil make you sleepy?

Sandalwood contains a substance called santalol, which appears to have potent sleep-inducing properties.

Can cannabinoids or terpenes cause insomnia?

Cannabinoids and terpenes will affect you differently based on your genetic code. That’s why testing your DNA is such an important component of choosing the cannabis-derived substances that are right for your specific genetics.

THC is especially well-known for causing adverse effects. In some people, THC may cause insomnia.

Will THC help you get to sleep, or will this intoxicating cannabinoid keep you up all night? Aside from painstaking trial and error, the only way to find out is to take a peek inside your genetic code.


Address insomnia naturally at the genetic level

Finally, there’s an alternative to switching from strain to strain or buying dozens of different CBD products online when you want to find out how specific cannabis-derived substances will affect your sleep. All it takes is:

  • Collecting your DNA with the EndoDNA Kit (or another qualifying genetic testing kit)
  • Uploading your DNA to the secure portal at mydna.live
  • Receiving your EndoDecoded Report, which will provide detailed information on the genetic basis on your insomnia and recommend specific products that match your DNA profile

Learn how to get a free EndoAligned Harlequin Hemp Oil Sweet Dreams tincture with an EndoDNA Kit.

With EndoDNA, you’ll find the certainty you need to tackle your insomnia naturally. Because—Everything Is Personal!

Endocanna Health is a biotechnology company committed to helping consumers find the right cannabinoid products to enhance their health and wellness. Using our breakthrough DNA test, Endo·dna, we empower you to take control of your health with access to over 55 different health reports that include suggestions for the best CBD and cannabis products that match your unique genetic code. Visit us here to find out more!